邻苯二醛(OPA)探针
邻苯二醛(OPA)探针是一种关键的功能化分子工具,主要应用于生物传感、环境监测及色谱分析三大领域,其核心优势在于高反应活性、共价交联稳定性及信号放大能力。
生物传感器构建——利用其双醛基与氨基的高效反应,作为交联剂固定酶(如漆酶)或核酸探针于电极表面,显著提升传感器稳定性与灵敏度;
环境污染物检测——通过修饰纳米材料(如磁性颗粒、MOFs)开发电化学/荧光传感器,实时检测水体中酚类化合物(邻苯二酚等)及重金属离子(Fe³⁺、Cr₂O₇²⁻);
色谱衍生化分析——与伯胺类物质(氨基酸、生物胺)在还原剂存在下生成强荧光衍生物,大幅增强HPLC对痕量目标物(如塑化剂、代谢氨基酸)的检测能力;
客户近期使用本公司产品发表的高影响因子论文(IF>10)
- Intelligent Nano-Cage for Precision Delivery of CRISPR-Cas9 and ACC Inhibitors to Enhance Antitumor Cascade Therapy Through Lipid Metabolism Disruption
- Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment
- A Versatile One-Step Enzymatic Strategy for Efficient Imaging and Mapping of Tumor-Associated Tn Antigen
- Surface-anchored tumor microenvironment-responsive protein nanogel-platelet system for cytosolic delivery of therapeutic protein in the post-surgical cancer treatment
- Genetically Incorporated Non-Canonical Amino Acids
- Boosting Dye-Sensitized Luminescence by Enhanced Short-Range Triplet Energy Transfer
- Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling
- Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling
- A proof-of-concept study on bioorthogonal-based pretargeting and signal amplify radiotheranostic strategy
- Bioengineered Platelets Combining Chemotherapy and Immunotherapy for Postsurgical Melanoma Treatment: Internal Core-Loaded Doxorubicin and External Surface-Anchored Anti-PDL1 Antibody Backpacks
- Scalable Synthesis of Highly Stable Cyclopropene Building Blocks: Application for Bioorthogonal Ligation with Tetrazines
- Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates
- Reversible control of tetrazine bioorthogonal reactivity by naphthotube-mediated host-guest recognition
- An Optimized Isotopic Photocleavable Tagging Strategy for SiteSpecific and Quantitative Profiling of Protein O‑GlcNAcylation in Colorectal Cancer Metastasis